A Secret Weapon For CUR61414
The impairment of HMGB1 perform contributes to amplified mitochondrial DNA problems. Within the SCA1 mouse model, in excess of-expression of the HMGB1 protein via an introduced virus vector bearing the HMGB1 gene facilitates maintenance from the mitochondrial DNA injury, ameliorates the neuropathology along with the motor deficits, and extends the